An educational tool to assist in the management of hepatic metastases in patients with colorectal cancer

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Chemotherapy for Colon Cancer

Influence of age on treatment options



If the patient had been in her late fifties instead of late thirties and had this same three lung nodule recurrence, I would have still used the same treatment, provided the fairly quick recurrence. If the lung nodules appeared two years after the chemotherapy had been received, I would have been more in favor of observing the patient and using chemotherapy at a time of further recurrent disease.


Use of FOLFIRI versus FOLFOX as treatment after prior FOLFOX

Commentator: STEVEN CURLEY, MD


Since the patient already received FOLFOX as adjuvant treatment after hemicolectomy, we felt that it would be better to use something new. Based on her K-ras wild-type status, FOLFIRI with cetuximab was selected because good responses have been shown in properly selected patients. Since she had had a full course of FOLFOX previously, the use of FOLFOX was not preferable when she developed metastatic disease.



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