An educational tool to assist in the management of hepatic metastases in patients with colorectal cancer

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Welcome to MetResect!

MetResect is an educational tool designed to help the clinician evaluate and treat patients with colorectal cancer that has metastasized to the liver but not more broadly, and for whom the basic clinical question is: Should the resection of the hepatic metastasis be attempted?

About one quarter of patients with colorectal disease will have hepatic metastases at the time of diagnosis and another quarter will develop such disease later. Although classical thinking has been that metastatic adenocarcinomas could not be cured, clinical work over the last three decades has shown this to be incorrect for patients with colorectal cancer metastatic only to the liver. About a third of such patients resected for cure will achieve long term complete remissions (> 5 years) and possible cure.

Other aspects of care for these patients with colorectal cancer metastatic to the liver have also matured. Roles for systemic and local chemotherapy and biological agents have been explored in terms of pre-operative roles (to allow conversion to resectability), as adjuvant, and as neoadjuvant therapy to improve outcome.

As outlined below MetResect provides illustrative cases which are discussed by experts in this field, and amongst which the user can select cases of particular relevance to clinical cases under their care. In addition MetResect supplies expert commentary about given clinical topics, and references and slide sets relevant to these topics.

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